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Gene Information
Gene ID:307644
Full Name:kinesin family member C3
Organism:Rattus norvegicus (Rat)
Genetic Location:19p13
Physical Location:10317917-10354363 on NC_005118.2
Gene Type:protein-coding
Human Ortholog:GeneID: 3801    Symbol (Name): KIFC3 (kinesin family member C3)
Ortholog Status:The human GeneID 3801 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Kifc3
Fold Change:-1.19
P Value:0.001
Note:Differential expression between ethanol and water groups in nucleus accumbens
Gene Information
Original ID1:Kifc3
Fold Change:-1.15
P Value:0.007
Note:Differential expression between ethanol and saccharin groups in nucleus accumbens
Dataset Information
Tissue:Nucleus accumbens and amygdala
Phenotype:Ethanol self-administration, alcohol-preferring
Publication:Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
XM_240978.4XP_240978.4NC_005118.2 range: 10317917..10354363
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005874microtubuleCellular ComponentIEA
GO:0005875microtubule associated complexCellular ComponentIEA
GO:0005794Golgi apparatusCellular ComponentISS
GO:0005871kinesin complexCellular ComponentISS
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0005524ATP bindingMolecular FunctionIEA
GO:0003777microtubule motor activityMolecular FunctionIEA
GO:0007017microtubule-based processBiological ProcessISS
GO:0007018microtubule-based movementBiological ProcessIEA
GO:0007030Golgi organization and biogenesisBiological ProcessISS
Other Database Cross Links
NCBI Entrez Gene:307644