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Gene Information
Gene ID:29600
Full Name:ATPase, Ca++ transporting, plasma membrane 4
Organism:Rattus norvegicus (Rat)
Genetic Location:13q13
Physical Location:46631204-46697213 on NC_005112.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 493    Symbol (Name): ATP2B4 (ATPase, Ca++ transporting, plasma membrane 4)
Ortholog Status:The human GeneID 493 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Atp2b4
Fold Change:-1.27
P Value:0.001
Note:Differential expression between ethanol and water groups in nucleus accumbens
Gene Information
Original ID1:Atp2b4
Fold Change:-1.25
P Value:0.002
Note:Differential expression between ethanol and saccharin groups in nucleus accumbens
Dataset Information
Tissue:Nucleus accumbens and amygdala
Phenotype:Ethanol self-administration, alcohol-preferring
Publication:Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001005871.1NP_001005871.1NC_005112.2 range: 46631204..46697213, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005887integral to plasma membraneCellular ComponentTAS (11779484)
GO:0005388calcium-transporting ATPase activityMolecular FunctionIDA (11779484)
GO:0030165PDZ domain bindingMolecular FunctionIPI (16554037)
GO:0030165PDZ domain bindingMolecular FunctionTAS (12511555)
GO:0006816calcium ion transportBiological ProcessIDA (11779484)
GO:0006874cellular calcium ion homeostasisBiological ProcessTAS (12511555)
GO:0019722calcium-mediated signalingBiological ProcessTAS (12511555)
Other Database Cross Links
NCBI Entrez Gene:29600