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Dataset Description
  • Dataset Name: 18405950
  • Species: Rat
  • Method: Microarray
  • No. of Genes: 444
  • Tissue: Nucleus accumbens and amygdala
  • Phenotype: Ethanol self-administration, alcohol-preferring
  • Publication: Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
  • Dataset Summary: The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.

    Gene list of this dataset (444 genes)
    Page: 1 2 3 4 5 6 7 8 9 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    140582Ddit4lDNA-damage-inducible transcript 4-like2q44Ddit4l 
    171574Dnm3dynamin 313q22Dnm3 
    286973Elavl2ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)5q32Elavl2 
    360891Enahenabled homolog (Drosophila)13q26Enah 
    56819Extl3exostoses (multiple)-like 315p12Extl3 
    84586Fgl2fibrinogen-like 24q11Fgl2 
    25451Gabrb2gamma-aminobutyric acid (GABA-A) receptor, subunit beta 210q21Gabrb2 
    24922Gabrb3gamma-aminobutyric acid (GABA-A) receptor, subunit beta 31q22Gabrb3 
    29627Gria2glutamate receptor, ionotropic, AMPA22q33Gria2 
    29628Gria3glutamate receptor, ionotropic, AMPA3 (alpha 3)Xq11Gria3 
    24379Gad1glutamic acid decarboxylase 13q21Gad1 
    24380Gad2glutamic acid decarboxylase 217q12.3Gad2 
    362173Caprin1cell cycle associated protein 13q32Gpiap1 
    81504Grb2growth factor receptor bound protein 210q32.3Grb2 
    81666Gnaqguanine nucleotide binding protein, alpha q polypeptide1q43Gnaq 
    81666Gnaqguanine nucleotide binding protein, alpha q polypeptide1q43Gnaq 
    116655Hnrpmheterogeneous nuclear ribonucleoprotein M7q12Hnrpm 
    25058Hk1hexokinase 120q11Hk1 
    25151Igf2rinsulin-like growth factor 2 receptor1q11Igf2r 
    361673Ifitm3interferon induced transmembrane protein 31q41Ifitm3 
    307644Kifc3kinesin family member C319p13Kifc3 
    362051Lmo4LIM domain only 42q44Lmo4 
    64472Mak10MAK10 homolog, amino-acid N-acetyltransferase subunit, (S. cerevisiae)17p14Mak10 
    29456Map1bmicrotubule-associated protein 1b2q12Map1b 
    361285Mllt10myeloid/lymphoid or mixed lineage-leukemia translocation to 10 homolog (Drosophila)17q12.3Mllt10 
    288280Ncam2neural cell adhesion molecule 211q11Ncam2 
    25489Nedd4neural precursor cell expressed, developmentally down-regulated gene 48q24Nedd4a 
    59315Nxph3neurexophilin 310q31Nxph3 
    29458Neurod1neurogenic differentiation 1-Neurod1 
    117041Nlnneurolysin (metallopeptidase M3 family)2q13Nln 
    298342NkapNFKB activating proteinXq122610020o08rik 
    25497Npap60nuclear pore associated protein7q34Npap60 
    25497Npap60nuclear pore associated protein7q34Npap60 
    245922Nupl1nucleoporin like 115p12Nupl1 
    29335Oprk1opioid receptor, kappa 15q12Oprk1 
    307774Otud4OTU domain containing 419q11Otud4 
    296461Osbpl2oxysterol binding protein-like 23q43Osbpl2 
    171435P34p34 protein8q24P34 
    60664Pik3r3phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)5q36Pik3r3 
    83572Pafah1b1platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa10q24Pafah1b1 
    116560Kcnj9potassium inwardly-rectifying channel, subfamily J, member 913q24Kcnj9 
    192256Pja2praja 2, RING-H2 motif containing9q37Pja2 
    24680Prkcaprotein kinase C, alpha10q32.1Prkca 
    293508Prkacbprotein kinase, cAMP dependent, catalytic, beta2q44Prkacb 
    29748Ppp3r1protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)14q22Ppp3r1 
    60586Clcn4-2chloride channel 4-2Xq21Clcn4-2 
    29434Rasgrp1RAS guanyl releasing protein 1-Rasgrp1 
    56820Ramp3receptor (calcitonin) activity modifying protein 314q21Ramp3 
    681377Rp1hretinitis pigmentosa 1 homolog (human)5q12Rp1h 
    29521Scamp1secretory carrier membrane protein 12q12Scamp1 
    Page: 1 2 3 4 5 6 7 8 9 list all