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Gene Information
Gene ID:84586
Symbol:Fgl2
Full Name:fibrinogen-like 2
Organism:Rattus norvegicus (Rat)
Chromosome:4
Genetic Location:4q11
Physical Location:9176332-9181975 on NC_005103.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 10875    Symbol (Name): FGL2 (fibrinogen-like 2)
Ortholog Status:The human GeneID 10875 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Fgl2
Fold Change:-1.19
P Value:0.01
Note:Differential expression between ethanol and saccharin groups in nucleus accumbens
Dataset Information
Name:18405950
Method:Microarray
Tissue:Nucleus accumbens and amygdala
Phenotype:Ethanol self-administration, alcohol-preferring
Publication:Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_053455.2NP_445907.2NC_005103.2 range: 9176332..9181975, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005102receptor bindingMolecular FunctionIEA
GO:0008233peptidase activityMolecular FunctionTAS (12593995)
GO:0007165signal transductionBiological ProcessIEA
GO:0007567parturitionBiological ProcessTAS (12593995)
Other Database Cross Links
NCBI Entrez Gene:84586
RGD:620170
Ensembl:ENSRNOG00000012881
dbSNP:Fgl2