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Dataset Description
  • Dataset Name: 18405950
  • Species: Rat
  • Method: Microarray
  • No. of Genes: 444
  • Tissue: Nucleus accumbens and amygdala
  • Phenotype: Ethanol self-administration, alcohol-preferring
  • Publication: Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
  • Dataset Summary: The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.

    Gene list of this dataset (444 genes)
    Page: 1 2 3 4 5 6 7 8 9 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    89812Pip4k2bphosphatidylinositol-5-phosphate 4-kinase, type II, beta10q31Pip5k2b 
    24689Prps2phosphoribosyl pyrophosphate synthetase 2Xq21Prps2 
    84429Kcnk9potassium channel, subfamily K, member 97q34Kcnk9 
    66022Kcns2potassium voltage-gated channel, delayed-rectifier, subfamily S, member 27q22Kcns2 
    117018Kcnh2potassium voltage-gated channel, subfamily H (eag-related), member 24q11Kcnh2 
    29682Kcnq3potassium voltage-gated channel, subfamily Q, member 37q33Kcnq3 
    25412Col2a1collagen, type II, alpha 17q36Col2a1 
    25204Pcsk1proprotein convertase subtilisin/kexin type 12q11-q12Pcsk1 
    24680Prkcaprotein kinase C, alpha10q32.1Prkca 
    64562Prkab2protein kinase, AMP-activated, beta 2 non-catalytic subunit2q34Prkab2 
    293508Prkacbprotein kinase, cAMP dependent, catalytic, beta2q44Prkacb 
    117281Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform1q12Ppp2r1a 
    56820Ramp3receptor (calcitonin) activity modifying protein 314q21Ramp3 
    24718Relnreelin4q11.2Reln 
    317241Rnf12ring finger protein 12Xq31Rnf12 
    360792Styxl1serine/threonine/tyrosine interacting-like 112q12Styxl1 
    294708Sgtbsmall glutamine-rich tetratricopeptide repeat (TPR)-containing, beta2q13Sgtb 
    25551Slc2a3solute carrier family 2 (facilitated glucose transporter), member 34q42Slc2a3 
    64037Slc22a4solute carrier family 22 (organic cation transporter), member 4-Slc22a4 
    25033Sstr1somatostatin receptor 16q23Sstr1 
    25547St8sia3ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 318q12.1St8sia3 
    29734Stchstress 70 protein chaperone, microsome-associated11p11Stch 
    60565Syt6synaptotagmin VI2q34Syt6 
    296182Txndc13thioredoxin domain containing 133q36Txndc13 
    498545Tsc22d1TSC22 domain family, member 115q11Tgfb1i4 
    58814Tmod2tropomodulin 28q24Tmod2 
    117557Tpm3tropomyosin 3, gamma2q34Tpm3 
    314442Warstryptophanyl-tRNA synthetase6q32Wars 
    301737Fert2fer (fms/fps related) protein kinase, testis specific 29q37Flk 
    408217Usp11ubiquitin specific peptidase 11Xq12Usp11 
    315608Ube4aubiquitination factor E4A, UFD2 homolog (S. cerevisiae)8q22Ube4a 
    65277Vti1avesicle transport through interaction with t-SNAREs homolog 1A (yeast)1q55Vti1a 
    310785Wdr47WD repeat domain 472q34Wdr47 
    114765Wbp4WW domain binding protein 415q12Wbp4 
    170955Znf483zinc finger protein 4835q24Zfp483 
    299211Zdhhc22zinc finger, DHHC-type containing 226q31Zdhhc22 
    299569Akap8lA kinase (PRKA) anchor protein 8-like7q11Akap8l 
    313917Abhd1abhydrolase domain containing 16q14Abhd1 
    79250Aco2aconitase 2, mitochondrial7q34Aco2 
    81634Actn1actinin, alpha 16q24Actn1 
    24186Albalbumin14p22Alb 
    140925As3mtarsenic (+3 oxidation state) methyltransferase1q54As3mt 
    170913Abcb1aATP-binding cassette, sub-family B (MDR/TAP), member 1A4q12Abcb1a 
    170924Abcc4ATP-binding cassette, sub-family C (CFTR/MRP), member 415q24Abcc4 
    29598Atp2b1ATPase, Ca++ transporting, plasma membrane 17q13Atp2b1 
    24223B2mbeta-2 microglobulin3q35B2m 
    24223B2mbeta-2 microglobulin3q35B2m 
    84407Cdh11cadherin 1119p14Cdh11 
    81823Cib1calcium and integrin binding 1 (calmyrin)1q31Cib1 
    306243Cacna2d3calcium channel, voltage-dependent, alpha2/delta subunit 316p16Cacna2d3 
    Page: 1 2 3 4 5 6 7 8 9 list all