ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Kcnk9

Full Name:

potassium channel, subfamily K, member 9

Alias:

Task3

Organism:

Rattus norvegicus (Rat)

Chromosome:

Genetic Location:

7q34

Physical Location:

110232400-110267635 on NC_005106.2, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 51305 Symbol (Name): KCNK9 (potassium channel, subfamily K, member 9)

Ortholog Status:

The human GeneID 51305 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Kcnk9
Fold Change:		-1.19
P Value:		0.003
Note:		Differential expression between ethanol and water groups in nucleus accumbens

Dataset Information

Name:		18405950
Method:		Microarray
Tissue:		Nucleus accumbens and amygdala
Phenotype:		Ethanol self-administration, alcohol-preferring
Publication:		Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:		The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_053405.2	NP_445857.2	NC_005106.2 range: 110232400..110267635, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016020	membrane	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0005244	voltage-gated ion channel activity	Molecular Function	IEA
GO:0005267	potassium channel activity	Molecular Function	IEA
GO:0030955	potassium ion binding	Molecular Function	IEA
GO:0006811	ion transport	Biological Process	IEA
GO:0006813	potassium ion transport	Biological Process	IEA