Home Search BLAST Integration Document Link Support Citation

Gene Information
Gene ID:360792
Full Name:serine/threonine/tyrosine interacting-like 1
Organism:Rattus norvegicus (Rat)
Genetic Location:12q12
Physical Location:22034610-22067319 on NC_005111.2
Gene Type:protein-coding
Human Ortholog:GeneID: 51657    Symbol (Name): STYXL1 (serine/threonine/tyrosine interacting-like 1)
Ortholog Status:The human GeneID 51657 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Styxl1
Fold Change:-1.22
P Value:0.001
Note:Differential expression between ethanol and water groups in nucleus accumbens
Gene Information
Original ID1:Styxl1
Fold Change:-1.17
P Value:0.007
Note:Differential expression between ethanol and saccharin groups in nucleus accumbens
Dataset Information
Tissue:Nucleus accumbens and amygdala
Phenotype:Ethanol self-administration, alcohol-preferring
Publication:Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001037788.1NP_001032877.1NC_005111.2 range: 22034610..22067319
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005515protein bindingMolecular FunctionISS
GO:0008138protein tyrosine/serine/threonine phosphatase activityMolecular FunctionIEA
GO:0006470protein amino acid dephosphorylationBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:360792