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Gene Information
Gene ID:29734
Symbol:Stch
Full Name:stress 70 protein chaperone, microsome-associated
Organism:Rattus norvegicus (Rat)
Chromosome:11
Genetic Location:11p11
Physical Location:14521609-14535914 on NC_005110.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 6782    Symbol (Name): STCH (stress 70 protein chaperone, microsome-associated, 60kDa)
Ortholog Status:The human GeneID 6782 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Stch
Fold Change:-1.16
P Value:0.003
Note:Differential expression between ethanol and water groups in nucleus accumbens
Gene Information
Original ID1:Stch
Fold Change:-1.2
P Value:0
Note:Differential expression between ethanol and saccharin groups in nucleus accumbens
Dataset Information
Name:18405950
Method:Microarray
Tissue:Nucleus accumbens and amygdala
Phenotype:Ethanol self-administration, alcohol-preferring
Publication:Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_019271.2NP_062144.2NC_005110.2 range: 14521609..14535914, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005783endoplasmic reticulumCellular ComponentIEA
GO:0005792microsomeCellular ComponentIEA
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0005524ATP bindingMolecular FunctionIEA
Other Database Cross Links
NCBI Entrez Gene:29734
RGD:3775
Ensembl:ENSRNOG00000032834
dbSNP:Stch