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Gene Information
Gene ID:317241
Symbol:Rnf12
Full Name:ring finger protein 12
Organism:Rattus norvegicus (Rat)
Chromosome:X
Genetic Location:Xq31
Physical Location:91969452-91985348 on NC_005120.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 51132    Symbol (Name): RNF12 (ring finger protein 12)
Ortholog Status:The human GeneID 51132 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Rnf12
Fold Change:-1.18
P Value:0.003
Note:Differential expression between ethanol and water groups in nucleus accumbens
Dataset Information
Name:18405950
Method:Microarray
Tissue:Nucleus accumbens and amygdala
Phenotype:Ethanol self-administration, alcohol-preferring
Publication:Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001024892.1NP_001020063.1NC_005120.2 range: 91969452..91985348, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0004842ubiquitin-protein ligase activityMolecular FunctionISS
GO:0005515protein bindingMolecular FunctionIEA
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
Other Database Cross Links
NCBI Entrez Gene:317241
RGD:1559832
Ensembl:ENSRNOG00000002824
dbSNP:Rnf12