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Dataset Description
  • Dataset Name: 18405950
  • Species: Rat
  • Method: Microarray
  • No. of Genes: 444
  • Tissue: Nucleus accumbens and amygdala
  • Phenotype: Ethanol self-administration, alcohol-preferring
  • Publication: Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
  • Dataset Summary: The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.

    Gene list of this dataset (444 genes)
    Page: 1 2 3 4 5 6 7 8 9 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    25252Dlgh1discs, large homolog 1 (Drosophila)11q22Dlgh1 
    64053Dlg2discs, large homolog 2 (Drosophila)1q32Dlgh2 
    171119DscamDown syndrome cell adhesion molecule11q12Dscam 
    116663Dusp6dual specificity phosphatase 67q13Dusp6 
    116651E2f5E2F transcription factor 52q23E2f5 
    114090Egr2early growth response 220p11Egr2 
    295490Emcnendomucin2q43Emcn 
    116744Lpar1lysophosphatidic acid receptor 15q24Edg2 
    84575Fads1fatty acid desaturase 11q43Fads1 
    50671Fasnfatty acid synthase-Fasn 
    314322FosFBJ osteosarcoma oncogene6q31Fos 
    29558FcgrtFc receptor, IgG, alpha chain transporter1q22Fcgrt 
    29292Ftl1ferritin light chain 11q22Ftl1 
    29752FauFinkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived) protein1q43Fau 
    64512Fzd2frizzled homolog 2 (Drosophila)10q32.1Fzd2 
    246299Gtf3ageneral transcription factor III A-Gtf3a 
    29328Gpx4glutathione peroxidase 47q11Gpx4 
    60666Gpd1glycerol-3-phosphate dehydrogenase 1 (soluble)7q36Gpd1 
    60666Gpd1glycerol-3-phosphate dehydrogenase 1 (soluble)7q36Gpd1 
    116727Gp1bbglycoprotein Ib, beta polypeptide11q23Gp1bb 
    282838Gm2aGM2 ganglioside activator protein10q22Gm2a 
    307288Gramd3GRAM domain containing 318q12.1Gramd3 
    25257Gamtguanidinoacetate methyltransferase7q11Gamt 
    29577Hes1hairy and enhancer of split 1 (Drosophila)11q22Hes1 
    79237Hhexhematopoietically expressed homeobox1q53Hhex 
    64627Hist1h4bhistone cluster 1, H4b17q11Hist1h4b 
    361796Bat5HLA-B associated transcript 520p12Bat5 
    29546Homer1homer homolog 1 (Drosophila)2q12Homer1 
    300993Hyal3hyaluronoglucosaminidase 38q32Hyal3 
    63864Hsd17b10hydroxysteroid (17-beta) dehydrogenase 10Xq21Hadh2 
    25116Hsd11b1hydroxysteroid 11-beta dehydrogenase 113q27Hsd11b1 
    84390Hcn1hyperpolarization-activated cyclic nucleotide-gated potassium channel 12q15Hcn1 
    282636Impa2inositol (myo)-1(or 4)-monophosphatase 218q12.1Impa2 
    116465Ifngr1interferon gamma receptor 11p12Ifngr 
    84405Il12ainterleukin 12a2q31Il12a 
    29245Klk6kallikrein related-peptidase 61q22Klk6 
    85497Klf15Kruppel-like factor 154q34Klf15 
    114505Klf4Kruppel-like factor 4 (gut)5q24Klf4 
    307858Ldhdlactate dehydrogenase D19q12Ldhd 
    307858Ldhdlactate dehydrogenase D19q12Ldhd 
    29150Matr3matrin 318p11Matr3 
    311456MkksMcKusick-Kaufman syndrome protein3q36Mkks 
    362849March2membrane-associated ring finger (C3HC4) 27q12MARCH2 
    117038Mt3metallothionein 319p12Mt3 
    353118MAST1microtubule associated serine/threonine kinase 119q11MAST1 
    25277Mfge8milk fat globule-EGF factor 8 protein1q31Mfge8 
    303200Map2k3mitogen activated protein kinase kinase 310q22Map2k3 
    29409Magmyelin-associated glycoprotein1q21Mag 
    25263Malmyelin and lymphocyte protein, T-cell differentiation protein3q36Mal 
    24558Mogmyelin oligodendrocyte glycoprotein20p12Mog 
    Page: 1 2 3 4 5 6 7 8 9 list all