ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

361796

Symbol:

Bat5

Full Name:

HLA-B associated transcript 5

Alias:

NG26

Organism:

Rattus norvegicus (Rat)

Chromosome:

Genetic Location:

20p12

Physical Location:

3782757-3797593 on NC_005119.2, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 7920 Symbol (Name): BAT5 (HLA-B associated transcript 5)

Ortholog Status:

The human GeneID 7920 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Bat5
Fold Change:		1.09
P Value:		0.009
Note:		Differential expression between ethanol and saccharin groups in nucleus accumbens

Dataset Information

Name:		18405950
Method:		Microarray
Tissue:		Nucleus accumbens and amygdala
Phenotype:		Ethanol self-administration, alcohol-preferring
Publication:		Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:		The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_212531.1	NP_997696.1	NC_005119.2 range: 3782757..3797593, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0030529	ribonucleoprotein complex	Cellular Component	IEA
GO:0005625	soluble fraction	Cellular Component	ISS
GO:0005624	membrane fraction	Cellular Component	ISS
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005576	extracellular region	Cellular Component	IDA
GO:0005737	cytoplasm	Cellular Component	ISS
GO:0016020	membrane	Cellular Component	IEA
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0008026	ATP-dependent helicase activity	Molecular Function	IEA
GO:0018024	histone-lysine N-methyltransferase activity	Molecular Function	IEA
GO:0008168	methyltransferase activity	Molecular Function	IEA
GO:0008233	peptidase activity	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	Molecular Function	IEA
GO:0016301	kinase activity	Molecular Function	IEA
GO:0003676	nucleic acid binding	Molecular Function	IEA
GO:0003677	DNA binding	Molecular Function	IEA
GO:0004252	serine-type endopeptidase activity	Molecular Function	IEA
GO:0004866	endopeptidase inhibitor activity	Molecular Function	IEA
GO:0005024	transforming growth factor beta receptor activity	Molecular Function	IEA
GO:0005247	voltage-gated chloride channel activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	ISS
GO:0005524	ATP binding	Molecular Function	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0045087	innate immune response	Biological Process	IEA
GO:0016568	chromatin modification	Biological Process	IEA
GO:0016071	mRNA metabolic process	Biological Process	IEA
GO:0006958	complement activation, classical pathway	Biological Process	NAS
GO:0006956	complement activation	Biological Process	IEA
GO:0006954	inflammatory response	Biological Process	NAS
GO:0006821	chloride transport	Biological Process	IEA
GO:0006508	proteolysis	Biological Process	IEA
GO:0045987	positive regulation of smooth muscle contraction	Biological Process	NAS