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Gene Information
Gene ID:85497
Symbol:Klf15
Full Name:Kruppel-like factor 15
Alias:MGC108619
Organism:Rattus norvegicus (Rat)
Chromosome:4
Genetic Location:4q34
Physical Location:124714394-124726990 on NC_005103.2
Gene Type:protein-coding
Human Ortholog:GeneID: 28999    Symbol (Name): KLF15 (Kruppel-like factor 15)
Ortholog Status:The human GeneID 28999 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Klf15
Fold Change:1.14
P Value:0.006
Note:Differential expression between ethanol and water groups in nucleus accumbens
Gene Information
Original ID1:Klf15
Fold Change:1.15
P Value:0.004
Note:Differential expression between ethanol and saccharin groups in nucleus accumbens
Dataset Information
Name:18405950
Method:Microarray
Tissue:Nucleus accumbens and amygdala
Phenotype:Ethanol self-administration, alcohol-preferring
Publication:Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_053536.1NP_445988.1NC_005103.2 range: 124714394..124726990
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005622intracellularCellular ComponentIEA
GO:0005634nucleusCellular ComponentISS
GO:0003676nucleic acid bindingMolecular FunctionIEA
GO:0003677DNA bindingMolecular FunctionISS
GO:0003700transcription factor activityMolecular FunctionISS
GO:0005515protein bindingMolecular FunctionISS
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0015758glucose transportBiological ProcessISS
GO:0045893positive regulation of transcription, DNA-dependentBiological ProcessISS
Other Database Cross Links
NCBI Entrez Gene:85497
RGD:70918
Ensembl:ENSRNOG00000017808
dbSNP:Klf15