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Gene Information
Gene ID:192256
Symbol:Pja2
Full Name:praja 2, RING-H2 motif containing
Alias:MGC91486|Neurodap1
Organism:Rattus norvegicus (Rat)
Chromosome:9
Genetic Location:9q37
Physical Location:103002777-103054006 on NC_005108.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 9867    Symbol (Name): PJA2 (praja 2, RING-H2 motif containing)
Ortholog Status:The human GeneID 9867 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Pja2
Fold Change:-1.16
P Value:0.001
Note:Differential expression between ethanol and saccharin groups in nucleus accumbens
Dataset Information
Name:18405950
Method:Microarray
Tissue:Nucleus accumbens and amygdala
Phenotype:Ethanol self-administration, alcohol-preferring
Publication:Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_138896.1NP_620251.1NC_005108.2 range: 103002777..103054006, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0000139Golgi membraneCellular ComponentIEA
GO:0045211postsynaptic membraneCellular ComponentIEA
GO:0045202synapseCellular ComponentIEA
GO:0005737cytoplasmCellular ComponentIEA
GO:0005783endoplasmic reticulumCellular ComponentIEA
GO:0005789endoplasmic reticulum membraneCellular ComponentIEA
GO:0005794Golgi apparatusCellular ComponentIEA
GO:0030054cell junctionCellular ComponentIEA
GO:0016874ligase activityMolecular FunctionIEA
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionISS
GO:0005515protein bindingMolecular FunctionIEA
GO:0006512ubiquitin cycleBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:192256
RGD:620273
Ensembl:ENSRNOG00000015528
dbSNP:Pja2