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Gene Information
Gene ID:171394
Full Name:calsyntenin 2
Organism:Rattus norvegicus (Rat)
Genetic Location:8q31
Physical Location:102328710-102347403 on NC_005107.2
Gene Type:protein-coding
Human Ortholog:GeneID: 64084    Symbol (Name): CLSTN2 (calsyntenin 2)
Ortholog Status:The human GeneID 64084 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Clstn2
Fold Change:-1.16
P Value:0.002
Note:Differential expression between ethanol and water groups in nucleus accumbens
Dataset Information
Tissue:Nucleus accumbens and amygdala
Phenotype:Ethanol self-administration, alcohol-preferring
Publication:Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_134377.1NP_599204.1NC_005107.2 range: 102328710..102347403
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005886plasma membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0045211postsynaptic membraneCellular ComponentIDA (12498782)
GO:0045211postsynaptic membraneCellular ComponentISS
GO:0005509calcium ion bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIEA
GO:0007155cell adhesionBiological ProcessIEA
GO:0007156homophilic cell adhesionBiological ProcessIEA
GO:0007268synaptic transmissionBiological ProcessNAS (12498782)
Other Database Cross Links
NCBI Entrez Gene:171394