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Gene Information
Gene ID:259274
Full Name:N-myristoyltransferase 1
Organism:Rattus norvegicus (Rat)
Genetic Location:10q32.1
Physical Location:92196639-92230570 on NC_005109.2
Gene Type:protein-coding
Human Ortholog:GeneID: 4836    Symbol (Name): NMT1 (N-myristoyltransferase 1)
Ortholog Status:The human GeneID 4836 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Nmt1
Fold Change:-1.14
P Value:0.005
Note:Differential expression between ethanol and water groups in nucleus accumbens
Dataset Information
Tissue:Nucleus accumbens and amygdala
Phenotype:Ethanol self-administration, alcohol-preferring
Publication:Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_148891.2NP_683689.1NC_005109.2 range: 92196639..92230570
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentIEA
GO:0019107myristoyltransferase activityMolecular FunctionIDA (12210757)
GO:0016740transferase activityMolecular FunctionIEA
GO:0004379glycylpeptide N-tetradecanoyltransferase activityMolecular FunctionIEA
GO:0004379glycylpeptide N-tetradecanoyltransferase activityMolecular FunctionISS
GO:0008415acyltransferase activityMolecular FunctionIEA
GO:0006499N-terminal protein myristoylationBiological ProcessISS
GO:0006499N-terminal protein myristoylationBiological ProcessIEA
GO:0001701in utero embryonic developmentBiological ProcessISS
GO:0001701in utero embryonic developmentBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:259274