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Gene Information
Gene ID:114636
Full Name:zyxin
Organism:Rattus norvegicus (Rat)
Genetic Location:4q23
Physical Location:70119040-70128080 on NC_005103.2
Gene Type:protein-coding
Human Ortholog:GeneID: 7791    Symbol (Name): ZYX (zyxin)
Ortholog Status:The human GeneID 7791 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Rn.87247
Original ID2:Zyx
Fold Change:2.16
P Value:0
Note:higher levels in hippocampus of iP than iNP rats
Dataset Information
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
Summary:The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
XM_216124.4XP_216124.3NC_005103.2 range: 70119040..70128080
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005913cell-cell adherens junctionCellular ComponentISS
GO:0005515protein bindingMolecular FunctionISS
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0050727regulation of inflammatory responseBiological ProcessIEP (11748220)
Other Database Cross Links
NCBI Entrez Gene:114636