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Dataset Description
  • Dataset Name: 15660665
  • Species: Rat
  • Method: Microarray
  • No. of Genes: 92
  • Tissue: Hippocampus
  • Phenotype: Alcohol-preferring, alcohol-nonpreferring
  • Publication: Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
  • Dataset Summary: The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01).

    Gene list of this dataset (92 genes)
    Page: 1 2 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    25450Gabrb1gamma-aminobutyric acid (GABA-A) receptor, subunit beta 114p11Rn.48879 
    65165Tmed2transmembrane emp24 domain trafficking protein 212q15Rn.22775Rnp24
    81574Scn1asodium channel, voltage-gated, type I, alpha3q21Rn.32079Scn1a
    65160Clns1achloride channel, nucleotide-sensitive, 1A1q32Rn.4089Clns1a
    65160Clns1achloride channel, nucleotide-sensitive, 1A1q32Rn.4089Clns1a
    29179Syn2synapsin II4q42Rn.506Syn2
    498549Akap11A kinase (PRKA) anchor protein 1115q11Rn.10557Akap11
    502603Sfrs11splicing factor, arginine/serine-rich 112q45Rn.11095Csnk2b
    64030Kitv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog14p11Rn.54004Kit
    64528Golga2golgi autoantigen, golgin subfamily a, 23p11Rn.6165Gm130
    60384Copb2coatomer protein complex, subunit beta 2 (beta prime)-Rn.37178Copb2
    81740Pcm1pericentriolar material 116q12.1Rn.19376Pcm1
    64192Qdprquinoid dihydropteridine reductase14q21Rn.241Qdpr
    64192Qdprquinoid dihydropteridine reductase14q21Rn.241Qdpr
    54315Ucp2uncoupling protein 2 (mitochondrial, proton carrier)1q32Rn.13333Ucp2
    54315Ucp2uncoupling protein 2 (mitochondrial, proton carrier)1q32Rn.13333Ucp2
    24424Gstm2glutathione S-transferase, mu 22q34Rn.625Gstm2
    79239Hmox2heme oxygenase (decycling) 210q12Rn.10241Hmox2
    60460Hspa2heat shock protein 26q24Rn.44325Hspt70
    58844Grb14growth factor receptor bound protein 143q21Rn.30028Grb14
    24387Gfapglial fibrillary acidic protein10q32.1 Gfap
    116565Lrpap1low density lipoprotein receptor-related protein associated protein 114q21Rn.10293Lrpap1
    24644Pgk1phosphoglycerate kinase 1Xq31Rn.3369Pgk1
    24192Akr1b1aldo-keto reductase family 1, member B1 (aldose reductase)4q22Rn.2917Aldr1
    81660Gatmglycine amidinotransferase (L-arginine:glycine amidinotransferase)3q35Rn.33427Gatm
    24188Aldh1a1aldehyde dehydrogenase 1 family, member A11q51Rn.6132Aldh1a1
    497778Dutdeoxyuridine triphosphatase3q36Rn.6102Dut
    116598Pdia4protein disulfide isomerase associated 44q24Rn.4070ERP70
    81643Atic5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase9q33Rn.15114Atic
    64514Eif2b1eukaryotic translation initiation factor 2B, subunit 1 alpha12q15Rn.9181Eif2b1
    83616Trim3tripartite motif-containing 31q33Rn.14524Trim3
    117152Cand1cullin associated and neddylation disassociated 17q22Rn.32934Tip120A
    25319Fth1ferritin heavy chain 11q43Rn.54447Fth1
    116967Magt1magnesium transporter 1Xq31Rn.43578IAG2
    64157Ddah1dimethylarginine dimethylaminohydrolase 12q44Rn.7398Ddah1
    294925Fndc3bfibronectin type III domain containing 3B2q24Rn.757 
    312656March8membrane-associated ring finger (C3HC4) 84q42Rn.3848 
    315447Chordc1cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 18q12Rn.6136 
    25652Ptgfrprostaglandin F receptor2q45Rn.54873Ptgfr
    29659P2rx4purinergic receptor P2X, ligand-gated ion channel 412q16Rn.7176P2rx4
    24379Gad1glutamic acid decarboxylase 13q21Rn.91245Gad1
    29686Scn1bsodium channel, voltage-gated, type I, beta1q21Rn.4958Scn1b
    Page: 1 2 list all