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Gene Information
Gene ID:65165
Full Name:transmembrane emp24 domain trafficking protein 2
Organism:Rattus norvegicus (Rat)
Genetic Location:12q15
Physical Location:33165287-33174325 on NC_005111.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 10959    Symbol (Name): TMED2 (transmembrane emp24 domain trafficking protein 2)
Ortholog Status:The human GeneID 10959 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Rn.22775
Original ID2:Rnp24
Fold Change:1.44
P Value:0.00043
Note:higher levels in hippocampus of iP than iNP rats
Dataset Information
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
Summary:The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_031722.2NP_113910.1NC_005111.2 range: 33165287..33174325, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0000139Golgi membraneCellular ComponentIEA
GO:0031410cytoplasmic vesicleCellular ComponentIEA
GO:0030659cytoplasmic vesicle membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIDA
GO:0016020membraneCellular ComponentIEA
GO:0042589zymogen granule membraneCellular ComponentIDA
GO:0005794Golgi apparatusCellular ComponentIEA
GO:0005793ER-Golgi intermediate compartmentCellular ComponentISS
GO:0005792microsomeCellular ComponentIDA
GO:0005515protein bindingMolecular FunctionISS
GO:0006886intracellular protein transportBiological ProcessNAS
GO:0006903vesicle targetingBiological ProcessNAS
Other Database Cross Links
NCBI Entrez Gene:65165