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Gene Information
Gene ID:79239
Full Name:heme oxygenase (decycling) 2
Organism:Rattus norvegicus (Rat)
Genetic Location:10q12
Physical Location:10914156-10929447 on NC_005109.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 3163    Symbol (Name): HMOX2 (heme oxygenase (decycling) 2)
Ortholog Status:The human GeneID 3163 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Rn.10241
Original ID2:Hmox2
Fold Change:1.27
P Value:0.00668
Note:higher levels in hippocampus of iP than iNP rats
Dataset Information
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
Summary:The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_024387.1NP_077363.1NC_005109.2 range: 10914156..10929447, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005792microsomeCellular ComponentIEA
GO:0005783endoplasmic reticulumCellular ComponentIEA
GO:0009055electron carrier activityMolecular FunctionISS
GO:0009055electron carrier activityMolecular FunctionIEA
GO:0004392heme oxygenase (decyclizing) activityMolecular FunctionIDA (2185251)
GO:0005506iron ion bindingMolecular FunctionIEA
GO:0004392heme oxygenase (decyclizing) activityMolecular FunctionTAS (12114211)
GO:0004392heme oxygenase (decyclizing) activityMolecular FunctionISS
GO:0004392heme oxygenase (decyclizing) activityMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0006788heme oxidationBiological ProcessIEA
GO:0006788heme oxidationBiological ProcessTAS (12114211)
GO:0006979response to oxidative stressBiological ProcessIDA (11950143)
Other Database Cross Links
NCBI Entrez Gene:79239