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Gene Information
Gene ID:60384
Full Name:coatomer protein complex, subunit beta 2 (beta prime)
Organism:Rattus norvegicus (Rat)
Gene Type:protein-coding
Human Ortholog:GeneID: 9276    Symbol (Name): COPB2 (coatomer protein complex, subunit beta 2 (beta prime))
Ortholog Status:The human GeneID 9276 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Rn.37178
Original ID2:Copb2
Fold Change:1.19
P Value:0.00954
Note:higher levels in hippocampus of iP than iNP rats
Dataset Information
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
Summary:The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01).
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0000139Golgi membraneCellular ComponentIDA (9360998)
GO:0030117membrane coatCellular ComponentIEA
GO:0030126COPI vesicle coatCellular ComponentISS
GO:0005794Golgi apparatusCellular ComponentISS
GO:0005515protein bindingMolecular FunctionISS
GO:0005515protein bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIDA (9360998)
GO:0005198structural molecule activityMolecular FunctionIEA
GO:0005080protein kinase C bindingMolecular FunctionIDA (9360998)
GO:0008565protein transporter activityMolecular FunctionIEA
GO:0006891intra-Golgi vesicle-mediated transportBiological ProcessISS
GO:0006886intracellular protein transportBiological ProcessIEA
GO:0006461protein complex assemblyBiological ProcessIEA
GO:0048193Golgi vesicle transportBiological ProcessIPI (9360998)
Other Database Cross Links
NCBI Entrez Gene:60384