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Gene Information
Gene ID:116565
Symbol:Lrpap1
Full Name:low density lipoprotein receptor-related protein associated protein 1
Organism:Rattus norvegicus (Rat)
Chromosome:14
Genetic Location:14q21
Physical Location:81292620-81306703 on NC_005113.2
Gene Type:protein-coding
Human Ortholog:GeneID: 4043    Symbol (Name): LRPAP1 (low density lipoprotein receptor-related protein associated protein 1)
Ortholog Status:The human GeneID 4043 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Rn.10293
Original ID2:Lrpap1
Fold Change:1.13
P Value:0.00922
Note:higher levels in hippocampus of iP than iNP rats
Dataset Information
Name:15660665
Method:Microarray
Tissue:Hippocampus
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
Summary:The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
XM_341239.2XP_341240.2NC_005113.2 range: 81292620..81306703
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentIEA
GO:0005783endoplasmic reticulumCellular ComponentIEA
GO:0005886plasma membraneCellular ComponentIEA
GO:0005886plasma membraneCellular ComponentISS
GO:0009986cell surfaceCellular ComponentIEA
GO:0031982vesicleCellular ComponentIDA (8223699)
GO:0048237rough endoplasmic reticulum lumenCellular ComponentIDA (8223699)
GO:0005515protein bindingMolecular FunctionIDA (16517593)
GO:0050750low-density lipoprotein receptor bindingMolecular FunctionIEA
GO:0008201heparin bindingMolecular FunctionIEA
GO:0050750low-density lipoprotein receptor bindingMolecular FunctionISS
Other Database Cross Links
NCBI Entrez Gene:116565
RGD:620700
Ensembl:ENSRNOG00000009313
dbSNP:Lrpap1