ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Fndc3b

Full Name:

fibronectin type III domain containing 3B

Alias:

RGD1311673

Organism:

Rattus norvegicus (Rat)

Chromosome:

Genetic Location:

2q24

Physical Location:

113312549-113558833 on NC_005101.2, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 64778 Symbol (Name): FNDC3B (fibronectin type III domain containing 3B)

Ortholog Status:

The human GeneID 64778 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Rn.757
Fold Change:		10.65
P Value:		0
Note:		higher levels in hippocampus of iP than iNP rats

Dataset Information

Name:		15660665
Method:		Microarray
Tissue:		Hippocampus
Phenotype:		Alcohol-preferring, alcohol-nonpreferring
Publication:		Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
Summary:		The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01).

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
XM_226988.4	XP_226988.3	NC_005101.2 range: 113312549..113558833, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0045600	positive regulation of fat cell differentiation	Biological Process	ISS