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Dataset Description
  • Dataset Name: 15660665
  • Species: Rat
  • Method: Microarray
  • No. of Genes: 92
  • Tissue: Hippocampus
  • Phenotype: Alcohol-preferring, alcohol-nonpreferring
  • Publication: Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
  • Dataset Summary: The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01).

    Gene list of this dataset (92 genes)
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    25450Gabrb1gamma-aminobutyric acid (GABA-A) receptor, subunit beta 114p11Rn.48879 
    65165Tmed2transmembrane emp24 domain trafficking protein 212q15Rn.22775Rnp24
    81574Scn1asodium channel, voltage-gated, type I, alpha3q21Rn.32079Scn1a
    65160Clns1achloride channel, nucleotide-sensitive, 1A1q32Rn.4089Clns1a
    65160Clns1achloride channel, nucleotide-sensitive, 1A1q32Rn.4089Clns1a
    29179Syn2synapsin II4q42Rn.506Syn2
    498549Akap11A kinase (PRKA) anchor protein 1115q11Rn.10557Akap11
    502603Sfrs11splicing factor, arginine/serine-rich 112q45Rn.11095Csnk2b
    64030Kitv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog14p11Rn.54004Kit
    64528Golga2golgi autoantigen, golgin subfamily a, 23p11Rn.6165Gm130
    60384Copb2coatomer protein complex, subunit beta 2 (beta prime)-Rn.37178Copb2
    81740Pcm1pericentriolar material 116q12.1Rn.19376Pcm1
    64192Qdprquinoid dihydropteridine reductase14q21Rn.241Qdpr
    64192Qdprquinoid dihydropteridine reductase14q21Rn.241Qdpr
    54315Ucp2uncoupling protein 2 (mitochondrial, proton carrier)1q32Rn.13333Ucp2
    54315Ucp2uncoupling protein 2 (mitochondrial, proton carrier)1q32Rn.13333Ucp2
    24424Gstm2glutathione S-transferase, mu 22q34Rn.625Gstm2
    79239Hmox2heme oxygenase (decycling) 210q12Rn.10241Hmox2
    60460Hspa2heat shock protein 26q24Rn.44325Hspt70
    114636Zyxzyxin4q23Rn.87247Zyx
    29139Dcndecorin7q13Rn.3819Dcn
    29139Dcndecorin7q13Rn.3819Dcn
    29139Dcndecorin7q13Rn.3819Dcn
    58844Grb14growth factor receptor bound protein 143q21Rn.30028Grb14
    24387Gfapglial fibrillary acidic protein10q32.1 Gfap
    116565Lrpap1low density lipoprotein receptor-related protein associated protein 114q21Rn.10293Lrpap1
    24644Pgk1phosphoglycerate kinase 1Xq31Rn.3369Pgk1
    24192Akr1b1aldo-keto reductase family 1, member B1 (aldose reductase)4q22Rn.2917Aldr1
    81660Gatmglycine amidinotransferase (L-arginine:glycine amidinotransferase)3q35Rn.33427Gatm
    24188Aldh1a1aldehyde dehydrogenase 1 family, member A11q51Rn.6132Aldh1a1
    497778Dutdeoxyuridine triphosphatase3q36Rn.6102Dut
    116598Pdia4protein disulfide isomerase associated 44q24Rn.4070ERP70
    81643Atic5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase9q33Rn.15114Atic
    64514Eif2b1eukaryotic translation initiation factor 2B, subunit 1 alpha12q15Rn.9181Eif2b1
    83616Trim3tripartite motif-containing 31q33Rn.14524Trim3
    117152Cand1cullin associated and neddylation disassociated 17q22Rn.32934Tip120A
        Rn.80836 
    25319Fth1ferritin heavy chain 11q43Rn.54447Fth1
    116967Magt1magnesium transporter 1Xq31Rn.43578IAG2
    64157Ddah1dimethylarginine dimethylaminohydrolase 12q44Rn.7398Ddah1
    294925Fndc3bfibronectin type III domain containing 3B2q24Rn.757 
        Rn.4264 
        Rn.14709 
    312656March8membrane-associated ring finger (C3HC4) 84q42Rn.3848 
    315447Chordc1cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 18q12Rn.6136 
        Rn.19047 
    25652Ptgfrprostaglandin F receptor2q45Rn.54873Ptgfr
    29659P2rx4purinergic receptor P2X, ligand-gated ion channel 412q16Rn.7176P2rx4
    24379Gad1glutamic acid decarboxylase 13q21Rn.91245Gad1
    29686Scn1bsodium channel, voltage-gated, type I, beta1q21Rn.4958Scn1b
    83471Prepprolyl endopeptidase20q13Rn.11058Prep
    83614Pias3protein inhibitor of activated STAT 32q34Rn.14548KChAP
    25520Prkag1protein kinase, AMP-activated, gamma 1 non-catalytic subunit7q36Rn.11089Prkag1
        Rn.6311 
    24166Adcyap1adenylate cyclase activating polypeptide 19q37Rn.37400Adcyap1
    117281Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform1q12Rn.4108Ppp2r1a
    81636Adcy2adenylate cyclase 217p14Rn.10731Adcy2
    64158Tuba1atubulin, alpha 1A7q36Rn.54749Tuba1
    65196B4galt6UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 618p12Rn.21126B4galt6
    171434Phldb1pleckstrin homology-like domain, family B, member 18q22Rn.11128Ll5
    25592Agrnagrin5q36Rn.2163Agrn
    79117Arf5ADP-ribosylation factor 54q22Rn.28244Arf5
    298696Pin1protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 18q13Rn.6291 
    308993Sephs2selenophosphate synthetase 21q36Rn.11447 
    58835Phgdh3-phosphoglycerate dehydrogenase2q34Rn.6872Phgdh
    140910Sc4molsterol-C4-methyl oxidase-like16p13Rn.7167Sc4mol
    24551Mdh1malate dehydrogenase 1, NAD (soluble)14q22Rn.1504Mdh1
    83842Crotcarnitine O-octanoyltransferase4q12Rn.4896Crot
    295443Papss13'-phosphoadenosine 5'-phosphosulfate synthase 12q43Rn.3507 
    24333Eno1enolase 1, alpha non-neuron5q36Rn.4236Eno1
    24189Aldoaaldolase A1q36Rn.1774Aldoa
    50654Ctsscathepsin S2q34Rn.11347Ctss
    64639Badbcl2-associated death promoter1q43Rn.36696Bad
    29318DdtD-dopachrome tautomerase20p12Rn.3464Ddt
    24737RT1-Aw2RT1 class Ib, locus Aw220p12Rn.83611 
    24737RT1-Aw2RT1 class Ib, locus Aw220p12Rn.39743RT1Aw2
    24737RT1-Aw2RT1 class Ib, locus Aw220p12Rn.39743RT1Aw2
    24737RT1-Aw2RT1 class Ib, locus Aw220p12Rn.39743RT1Aw2
    25584F3coagulation factor III2q41Rn.9980F3
    83789Rps2ribosomal protein S210q12Rn.2115Rps2
    171451Mosc2MOCO sulphurase C-terminal domain containing 213q26Rn.11802Mg87
    116646Tpt1tumor protein, translationally-controlled 115q11Rn.36610Tpt1
    24822Tegttestis enhanced gene transcript7q36Rn.98Tegt
    24737RT1-Aw2RT1 class Ib, locus Aw220p12Rn.39743RT1Aw2
    245924Sfrs15splicing factor, arginine/serine-rich 1511q11Rn.101886 
        Rn.806 
    25261Id1inhibitor of DNA binding 13q41Rn.2113Id1
    25233Akt2thymoma viral proto-oncogene 21q22Rn.87066Akt2
    170944Dkc1dyskeratosis congenita 1, dyskerin-Rn.4223Dkc1
        Rn.3901 
    24825Trftransferrin8q32Rn.32307 
        Rn.21416 
    361726RGD1309216similar to hypothetical protein FLJ204871q43Rn.3529 
    298712RGD1307254similar to RIKEN cDNA 1200011I1815q11Rn.22071 
        Rn.19944 
        Rn.42056 
    314330RGD1309492similar to mKIAA1737 protein6q31Rn.19617 
        Rn.52727 
        Rn.13170 
        Rn.3719 
        Rn.86988 
        Rn.8165 
        Rn.4287 
    361813Stk38serine/threonine kinase 3820p12Rn.13142 
        Rn.19709 
        Rn.3068 
        Rn.268 
    24170Add1adducin 1 (alpha)14q21Rn.34234 
    360820Pxnpaxillin12q16Rn.75 
    363278Atg16l1autophagy-related 16-like 1 (yeast)9q35Rn.8130 
    29468Pdia3protein disulfide isomerase associated 33q35Rn.11527 
    300222Mcrs1microspherule protein 17q36Rn.2727 
    361215AuhAU RNA binding protein/enoyl-coenzyme A hydratase17p14Rn.50 
        Rn.14797 
        Rn.4060 
        Rn.40386 
        Rn.22765 
        Rn.43551 
    306587TctaT-cell leukemia translocation altered gene16q12.5Rn.2916 
    313529Tmem53transmembrane protein 535q36Rn.8133 
    361102Polr3apolymerase (RNA) III (DNA directed) polypeptide A16p16Rn.41904 
    306204Flnbfilamin, beta15p14Rn.1761 
    308879RGD1561159similar to TRNA nucleotidyl transferase, CCA-adding, 11q35Rn.1530 
    362790RGD1308350similar to hypothetical protein MGC132516q32Rn.2343 
        Rn.19948