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Gene Information
Gene ID:24166
Symbol:Adcyap1
Full Name:adenylate cyclase activating polypeptide 1
Alias:Pacap
Organism:Rattus norvegicus (Rat)
Chromosome:9
Genetic Location:9q37
Gene Type:protein-coding
Human Ortholog:GeneID: 116    Symbol (Name): ADCYAP1 (adenylate cyclase activating polypeptide 1 (pituitary))
Ortholog Status:The human GeneID 116 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Rn.37400
Original ID2:Adcyap1
Fold Change:1.3
P Value:0.00701
Note:Lower levels in the hippocampus of iP than iNP rats
Dataset Information
Name:15660665
Method:Microarray
Tissue:Hippocampus
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
Summary:The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01).
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005576extracellular regionCellular ComponentIEA
GO:0005057receptor signaling protein activityMolecular FunctionISS
GO:0005179hormone activityMolecular FunctionIEA
GO:0007218neuropeptide signaling pathwayBiological ProcessNAS (11959368)
GO:0045786negative regulation of cell cycleBiological ProcessISS
Other Database Cross Links
NCBI Entrez Gene:24166
RGD:2037
Ensembl:
dbSNP:Adcyap1