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Gene Information
Gene ID:306204
Full Name:filamin, beta
Organism:Rattus norvegicus (Rat)
Genetic Location:15p14
Physical Location:18949022-19082574 on NC_005114.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 2317    Symbol (Name): FLNB (filamin B, beta (actin binding protein 278))
Ortholog Status:The human GeneID 2317 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Rn.1761
Fold Change:1.2
P Value:0.00758
Note:Lower levels in the hippocampus of iP than iNP rats
Dataset Information
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
Summary:The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
XM_224561.4XP_224561.4NC_005114.2 range: 18949022..19082574, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0001725stress fiberCellular ComponentISS
GO:0005575cellular_componentCellular ComponentND
GO:0005925focal adhesionCellular ComponentISS
GO:0003674molecular_functionMolecular FunctionND
GO:0005515protein bindingMolecular FunctionISS
GO:0007519skeletal muscle developmentBiological ProcessISS
GO:0008150biological_processBiological ProcessND
Other Database Cross Links
NCBI Entrez Gene:306204