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Gene Information
Gene ID:245924
Symbol:Sfrs15
Full Name:splicing factor, arginine/serine-rich 15
Organism:Rattus norvegicus (Rat)
Chromosome:11
Genetic Location:11q11
Physical Location:29714058-29808186 on NC_005110.2
Gene Type:protein-coding
Human Ortholog:This gene has no human ortholog.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Rn.101886
Fold Change:1.27
P Value:0.00245
Note:Lower levels in the hippocampus of iP than iNP rats
Dataset Information
Name:15660665
Method:Microarray
Tissue:Hippocampus
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
Summary:The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
XM_213658.4XP_213658.4NC_005110.2 range: 29714058..29808186
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0003676nucleic acid bindingMolecular FunctionIEA
GO:0003723RNA bindingMolecular FunctionIEA
GO:0008022protein C-terminus bindingMolecular FunctionIPI (8692929)
GO:0006397mRNA processingBiological ProcessIMP (8692929)
Other Database Cross Links
NCBI Entrez Gene:245924
RGD:727896
Ensembl:ENSRNOG00000002104
dbSNP:Sfrs15