ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Auh

Full Name:

AU RNA binding protein/enoyl-coenzyme A hydratase

Organism:

Rattus norvegicus (Rat)

Chromosome:

Genetic Location:

17p14

Physical Location:

18141879-18251865 on NC_005116.2

Gene Type:

protein-coding

Human Ortholog:

GeneID: 549 Symbol (Name): AUH (AU RNA binding protein/enoyl-Coenzyme A hydratase)

Ortholog Status:

The human GeneID 549 is also in human dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Rn.50
Fold Change:		1.16
P Value:		0.00427
Note:		Lower levels in the hippocampus of iP than iNP rats

Dataset Information

Name:		15660665
Method:		Microarray
Tissue:		Hippocampus
Phenotype:		Alcohol-preferring, alcohol-nonpreferring
Publication:		Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
Summary:		The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01).

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
XM_341497.3	XP_341498.1	NC_005116.2 range: 18141879..18251865

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005575	cellular_component	Cellular Component	ND
GO:0005739	mitochondrion	Cellular Component	ISS
GO:0003674	molecular_function	Molecular Function	ND
GO:0003723	RNA binding	Molecular Function	ISS
GO:0004300	enoyl-CoA hydratase activity	Molecular Function	ISS
GO:0008150	biological_process	Biological Process	ND