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Gene Information
Gene ID:313529
Symbol:Tmem53
Full Name:transmembrane protein 53
Alias:RGD1307066
Organism:Rattus norvegicus (Rat)
Chromosome:5
Genetic Location:5q36
Physical Location:137559857-137575394 on NC_005104.2
Gene Type:protein-coding
Human Ortholog:GeneID: 79639    Symbol (Name): TMEM53 (transmembrane protein 53)
Ortholog Status:The human GeneID 79639 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Rn.8133
Fold Change:1.14
P Value:0.00647
Note:Lower levels in the hippocampus of iP than iNP rats
Dataset Information
Name:15660665
Method:Microarray
Tissue:Hippocampus
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
Summary:The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
XM_233431.4XP_233431.2NC_005104.2 range: 137559857..137575394
Other Database Cross Links
NCBI Entrez Gene:313529
RGD:1307066
Ensembl:ENSRNOG00000019186
dbSNP:Tmem53