| Gene Information |
| Gene ID: | | 360820 |
| Symbol: | | Pxn |
| Full Name: | | paxillin |
| Organism: | | Rattus norvegicus (Rat) |
| Chromosome: | | 12 |
| Genetic Location: | | 12q16 |
| Physical Location: | | 42322192-42370506 on NC_005111.2, complement |
| Gene Type: | | protein-coding |
| Human Ortholog: | | This gene has no human ortholog. |
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| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID1: | | Rn.75 | | Fold Change: | | 1.23 | | P Value: | | 0.00257 | | Note: | | Lower levels in the hippocampus of iP than iNP rats |
| | Dataset Information | | Name: | | 15660665 | | Method: | | Microarray | | Tissue: | | Hippocampus | | Phenotype: | | Alcohol-preferring, alcohol-nonpreferring | | Publication: | | Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed | | Summary: | | The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01). |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0005737 | cytoplasm | Cellular Component | IEA | |
| GO:0005856 | cytoskeleton | Cellular Component | IEA | |
| GO:0030054 | cell junction | Cellular Component | IEA | |
| GO:0005515 | protein binding | Molecular Function | IEA | |
| GO:0008270 | zinc ion binding | Molecular Function | IEA | |
| GO:0046872 | metal ion binding | Molecular Function | IEA | |
| GO:0007155 | cell adhesion | Biological Process | IEA | |
| GO:0007160 | cell-matrix adhesion | Biological Process | IEA | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 360820 |
| RGD: | | 1305759 |
| Ensembl: | | ENSRNOG00000001149 |
| dbSNP: | | Pxn |
