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Gene Information
Gene ID:81660
Symbol:Gatm
Full Name:glycine amidinotransferase (L-arginine:glycine amidinotransferase)
Alias:MGC93388
Organism:Rattus norvegicus (Rat)
Chromosome:3
Genetic Location:3q35
Physical Location:109558012-109565492 on NC_005102.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 2628    Symbol (Name): GATM (glycine amidinotransferase (L-arginine:glycine amidinotransferase))
Ortholog Status:The human GeneID 2628 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Rn.33427
Original ID2:Gatm
Fold Change:1.36
P Value:0.00027
Note:higher levels in hippocampus of iP than iNP rats
Dataset Information
Name:15660665
Method:Microarray
Tissue:Hippocampus
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
Summary:The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
XM_575224.1XP_575224.1NC_005102.2 range: 109558012..109565492, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005575cellular_componentCellular ComponentND
GO:0005739mitochondrionCellular ComponentISS
GO:0005758mitochondrial intermembrane spaceCellular ComponentISS
GO:0016740transferase activityMolecular FunctionIEA
GO:0015068glycine amidinotransferase activityMolecular FunctionISS
GO:0015067amidinotransferase activityMolecular FunctionIDA (8035648)
GO:0043434response to peptide hormone stimulusBiological ProcessIDA (8021264)
GO:0042246tissue regenerationBiological ProcessIEP (16626512)
GO:0010033response to organic substanceBiological ProcessIDA (15600250)
GO:0009790embryonic developmentBiological ProcessIEP (15918910)
GO:0007584response to nutrientBiological ProcessIDA (11595668)
GO:0006979response to oxidative stressBiological ProcessIEP (8837048)
GO:0006601creatine biosynthetic processBiological ProcessTAS (8021264)
GO:0006601creatine biosynthetic processBiological ProcessISS
GO:0046689response to mercury ionBiological ProcessIDA (15600250)
Other Database Cross Links
NCBI Entrez Gene:81660
RGD:71090
Ensembl:ENSRNOG00000000168
dbSNP:Gatm