ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Tegt

Full Name:

testis enhanced gene transcript

Alias:

Ab1-011|Ac1-149|Cc1-27

Organism:

Rattus norvegicus (Rat)

Chromosome:

Genetic Location:

7q36

Physical Location:

138116341-138155714 on NC_005106.2

Gene Type:

protein-coding

Human Ortholog:

GeneID: 7009 Symbol (Name): TEGT (testis enhanced gene transcript (BAX inhibitor 1))

Ortholog Status:

The human GeneID 7009 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Rn.98
Original ID2:		Tegt
Fold Change:		1.22
P Value:		0.00078
Note:		Lower levels in the hippocampus of iP than iNP rats

Dataset Information

Name:		15660665
Method:		Microarray
Tissue:		Hippocampus
Phenotype:		Alcohol-preferring, alcohol-nonpreferring
Publication:		Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
Summary:		The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01).

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
XM_576343.2	XP_576343.1	NC_005106.2 range: 138116341..138155714

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0007283	spermatogenesis	Biological Process	IEP (8012111)
GO:0043066	negative regulation of apoptosis	Biological Process	IEA