ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Ctss

Full Name:

cathepsin S

Organism:

Rattus norvegicus (Rat)

Chromosome:

Genetic Location:

2q34

Physical Location:

190422637-190466876 on NC_005101.2

Gene Type:

protein-coding

Human Ortholog:

GeneID: 1520 Symbol (Name): CTSS (cathepsin S)

Ortholog Status:

The human GeneID 1520 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Rn.11347
Original ID2:		Ctss
Fold Change:		1.22
P Value:		0.00015
Note:		Lower levels in the hippocampus of iP than iNP rats

Dataset Information

Name:		15660665
Method:		Microarray
Tissue:		Hippocampus
Phenotype:		Alcohol-preferring, alcohol-nonpreferring
Publication:		Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
Summary:		The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01).

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_017320.1	NP_059016.1	NC_005101.2 range: 190422637..190466876

Gene Ontology (GO) Annotation