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Gene Information
Gene ID:116646
Full Name:tumor protein, translationally-controlled 1
Organism:Rattus norvegicus (Rat)
Genetic Location:15q11
Physical Location:56752463-56755287 on NC_005114.2
Gene Type:protein-coding
Human Ortholog:GeneID: 7178    Symbol (Name): TPT1 (tumor protein, translationally-controlled 1)
Ortholog Status:The human GeneID 7178 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Rn.36610
Original ID2:Tpt1
Fold Change:1.31
P Value:0.00065
Note:Lower levels in the hippocampus of iP than iNP rats
Dataset Information
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
Summary:The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_053867.1NP_446319.1NC_005114.2 range: 56752463..56755287
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0045298tubulin complexCellular ComponentISS
GO:0005771multivesicular bodyCellular ComponentISS
GO:0005737cytoplasmCellular ComponentISS
GO:0005737cytoplasmCellular ComponentIEA
GO:0005615extracellular spaceCellular ComponentISS
GO:0005515protein bindingMolecular FunctionISS
GO:0005509calcium ion bindingMolecular FunctionISS
GO:0005509calcium ion bindingMolecular FunctionIEA
GO:0006916anti-apoptosisBiological ProcessISS
GO:0007283spermatogenesisBiological ProcessIEP (11503212)
GO:0008283cell proliferationBiological ProcessTAS (11503212)
Other Database Cross Links
NCBI Entrez Gene:116646