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Gene Information
Gene ID:79117
Full Name:ADP-ribosylation factor 5
Organism:Rattus norvegicus (Rat)
Genetic Location:4q22
Physical Location:55293824-55296750 on NC_005103.2
Gene Type:protein-coding
Human Ortholog:GeneID: 381    Symbol (Name): ARF5 (ADP-ribosylation factor 5)
Ortholog Status:The human GeneID 381 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Rn.28244
Original ID2:Arf5
Fold Change:1.09
P Value:0.00812
Note:Lower levels in the hippocampus of iP than iNP rats
Dataset Information
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
Summary:The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_024149.1NP_077063.1NC_005103.2 range: 55293824..55296750
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005794Golgi apparatusCellular ComponentIEA
GO:0005886plasma membraneCellular ComponentISS
GO:0005622intracellularCellular ComponentIEA
GO:0005737cytoplasmCellular ComponentIEA
GO:0005737cytoplasmCellular ComponentISS
GO:0005886plasma membraneCellular ComponentIEA
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0005525GTP bindingMolecular FunctionIEA
GO:0007264small GTPase mediated signal transductionBiological ProcessIEA
GO:0015031protein transportBiological ProcessIEA
GO:0016192vesicle-mediated transportBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:79117