ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Clns1a

Full Name:

chloride channel, nucleotide-sensitive, 1A

Alias:

Clci|Clcni|Icln|pICln

Organism:

Rattus norvegicus (Rat)

Chromosome:

Genetic Location:

1q32

Physical Location:

154946712-154966946 on NC_005100.2

Gene Type:

protein-coding

Human Ortholog:

GeneID: 1207 Symbol (Name): CLNS1A (chloride channel, nucleotide-sensitive, 1A)

Ortholog Status:

The human GeneID 1207 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Rn.4089
Original ID2:		Clns1a
Fold Change:		1.3
P Value:		0.00137
Note:		higher levels in hippocampus of iP than iNP rats

Gene Information

Original ID1:		Rn.4089
Original ID2:		Clns1a
Fold Change:		1.26
P Value:		0.00642
Note:		higher levels in hippocampus of iP than iNP rats

Dataset Information

Name:		15660665
Method:		Microarray
Tissue:		Hippocampus
Phenotype:		Alcohol-preferring, alcohol-nonpreferring
Publication:		Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
Summary:		The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01).

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_031719.1	NP_113907.1	NC_005100.2 range: 154946712..154966946

Gene Ontology (GO) Annotation