Gene Information |
Gene ID: | | 171434 |
Symbol: | | Phldb1 |
Full Name: | | pleckstrin homology-like domain, family B, member 1 |
Alias: | | Ll5 |
Organism: | | Rattus norvegicus (Rat) |
Chromosome: | | 8 |
Genetic Location: | | 8q22 |
Physical Location: | | 47645163-47693361 on NC_005107.2, complement |
Gene Type: | | protein-coding |
Human Ortholog: | | GeneID: 23187 Symbol (Name): PHLDB1 (pleckstrin homology-like domain, family B, member 1) |
Ortholog Status: | | The human GeneID 23187 is not in current human dataset. |
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Gene in Ethanol Study Datasets |
Gene Information | Original ID1: | | Rn.11128 | Original ID2: | | Ll5 | Fold Change: | | 1.25 | P Value: | | 0.00009 | Note: | | Lower levels in the hippocampus of iP than iNP rats |
| Dataset Information | Name: | | 15660665 | Method: | | Microarray | Tissue: | | Hippocampus | Phenotype: | | Alcohol-preferring, alcohol-nonpreferring | Publication: | | Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed | Summary: | | The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01). |
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Gene Refseq Sequence Annotation |
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Other Database Cross Links |
NCBI Entrez Gene: | | 171434 |
RGD: | | 620878 |
Ensembl: | | ENSRNOG00000026985 |
dbSNP: | | Phldb1 |