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Gene Information
Gene ID:171434
Full Name:pleckstrin homology-like domain, family B, member 1
Organism:Rattus norvegicus (Rat)
Genetic Location:8q22
Physical Location:47645163-47693361 on NC_005107.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 23187    Symbol (Name): PHLDB1 (pleckstrin homology-like domain, family B, member 1)
Ortholog Status:The human GeneID 23187 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Rn.11128
Original ID2:Ll5
Fold Change:1.25
P Value:0.00009
Note:Lower levels in the hippocampus of iP than iNP rats
Dataset Information
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
Summary:The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
XM_576401.2XP_576401.2NC_005107.2 range: 47645163..47693361, complement
Other Database Cross Links
NCBI Entrez Gene:171434