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Gene Information
Gene ID:24825
Full Name:transferrin
Organism:Rattus norvegicus (Rat)
Genetic Location:8q32
Physical Location:108217773-108244486 on NC_005107.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 7018    Symbol (Name): TF (transferrin)
Ortholog Status:The human GeneID 7018 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Rn.32307
Fold Change:2.95
P Value:0
Note:Lower levels in the hippocampus of iP than iNP rats
Dataset Information
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
Summary:The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001013110.1NP_001013128.1NC_005107.2 range: 108217773..108244486, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005604basement membraneCellular ComponentIDA (1723977)
GO:0005615extracellular spaceCellular ComponentIDA (17350134)
GO:0005768endosomeCellular ComponentISS
GO:0030139endocytic vesicleCellular ComponentISS
GO:0015091ferric iron transmembrane transporter activityMolecular FunctionIDA (17373738)
GO:0008199ferric iron bindingMolecular FunctionIDA (17373738)
GO:0001666response to hypoxiaBiological ProcessIEP (16479386)
GO:0015682ferric iron transportBiological ProcessIDA (17373738)
GO:0014070response to organic cyclic substanceBiological ProcessIEP (16519141)
GO:0006953acute-phase responseBiological ProcessIEP (17417667)
GO:0006879cellular iron ion homeostasisBiological ProcessTAS (12608731)
GO:0006826iron ion transportBiological ProcessTAS (12608731)
GO:0031643positive regulation of myelinationBiological ProcessIDA (16480980)
Other Database Cross Links
NCBI Entrez Gene:24825