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Gene Information
Gene ID:171451
Full Name:MOCO sulphurase C-terminal domain containing 2
Organism:Rattus norvegicus (Rat)
Genetic Location:13q26
Physical Location:100809305-100838647 on NC_005112.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 54996    Symbol (Name): MOSC2 (MOCO sulphurase C-terminal domain containing 2)
Ortholog Status:The human GeneID 54996 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Rn.11802
Original ID2:Mg87
Fold Change:1.36
P Value:0.00021
Note:Lower levels in the hippocampus of iP than iNP rats
Dataset Information
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
Summary:The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_134410.1NP_599237.1NC_005112.2 range: 100809305..100838647, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005739mitochondrionCellular ComponentISS
GO:0005741mitochondrial outer membraneCellular ComponentIEA
GO:0005743mitochondrial inner membraneCellular ComponentISS
GO:0016020membraneCellular ComponentIEA
GO:0019867outer membraneCellular ComponentIEA
GO:0016491oxidoreductase activityMolecular FunctionIEA
GO:0030151molybdenum ion bindingMolecular FunctionIEA
GO:0030170pyridoxal phosphate bindingMolecular FunctionIEA
Other Database Cross Links
NCBI Entrez Gene:171451