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Gene Information
Gene ID:306587
Full Name:T-cell leukemia translocation altered gene
Organism:Rattus norvegicus (Rat)
Genetic Location:16q12.5
Gene Type:protein-coding
Human Ortholog:GeneID: 6988    Symbol (Name): TCTA (T-cell leukemia translocation altered gene)
Ortholog Status:The human GeneID 6988 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Rn.2916
Fold Change:1.17
P Value:0.00611
Note:Lower levels in the hippocampus of iP than iNP rats
Dataset Information
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Edenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
Summary:The objective of this study was to test the hypothesis that there are innate differences in gene expression in the hippocampus of inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats that may contribute to differences in sensitivity to ethanol and/or in the development of tolerance. Affymetrix microarrays were used to measure gene expression in the hippocampus of alcohol-naive male iP and iNP rats in two experiments (n = 4 and 6 per strain in the two experiments). Combining data from the two experiments, there were 137 probesets representing 129 genes that significantly differed (P ? 0.01).
Other Database Cross Links
NCBI Entrez Gene:306587