ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Parp1

Full Name:

poly (ADP-ribose) polymerase family, member 1

Alias:

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 H5|1 98.6 cM

Physical Location:

182499105-182531384 on NC_000067.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 142 Symbol (Name): PARP1 (poly (ADP-ribose) polymerase family, member 1)

Ortholog Status:

The human GeneID 142 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Calw1/Alcdp1	Chronic Alcohol Withdrawal	1	96	89-106.3 (cM)	7.6	2.00E-09	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_007415.2	NP_031441.2	NC_000067.5 range: 182499105..182531384

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	TAS (12065591)
GO:0005622	intracellular	Cellular Component	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0016757	transferase activity, transferring glycosyl groups	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0051287	NAD binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (14627987)
GO:0003950	NAD+ ADP-ribosyltransferase activity	Molecular Function	IEA
GO:0003677	DNA binding	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0040009	regulation of growth rate	Biological Process	IMP (12707040)
GO:0006974	response to DNA damage stimulus	Biological Process	IEA
GO:0006471	protein amino acid ADP-ribosylation	Biological Process	IEA
GO:0006284	base-excision repair	Biological Process	IMP (11948190)
GO:0006281	DNA repair	Biological Process	TAS (12065591)
GO:0006259	DNA metabolic process	Biological Process	IMP (11756244\|12707040)
GO:0000723	telomere maintenance	Biological Process	IMP (12707040)