ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

PARP1

Full Name:

poly (ADP-ribose) polymerase family, member 1

Alias:

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

1q41-q42

Physical Location:

224615014-224662423 on NC_000001.9, complement

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 11545 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

PARP1

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001618.3	NP_001609.2	NC_000001.9 range: 224615014..224662423, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	TAS (2513174)
GO:0005622	intracellular	Cellular Component	IEA
GO:0005634	nucleus	Cellular Component	IEA
GO:0005730	nucleolus	Cellular Component	IDA (9518481\|16107709)
GO:0005635	nuclear envelope	Cellular Component	IDA (9518481)
GO:0016757	transferase activity, transferring glycosyl groups	Molecular Function	IEA
GO:0042802	identical protein binding	Molecular Function	IPI (14734561)
GO:0003677	DNA binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0047485	protein N-terminus binding	Molecular Function	IPI (16107709)
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0051287	NAD binding	Molecular Function	IEA
GO:0003950	NAD+ ADP-ribosyltransferase activity	Molecular Function	IDA (16107709)
GO:0003677	DNA binding	Molecular Function	TAS (2513174)
GO:0006471	protein amino acid ADP-ribosylation	Biological Process	TAS (2513174)
GO:0006366	transcription from RNA polymerase II promoter	Biological Process	TAS (10944198)
GO:0006281	DNA repair	Biological Process	TAS (10958667)