ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Apoa2

Full Name:

apolipoprotein A-II

Alias:

Alp-2|ApoA-II|ApoAII|Apoa-2|Hdl-1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 H3|1 92.6 cM

Physical Location:

173155219-173156500 on NC_000067.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 336 Symbol (Name): APOA2 (apolipoprotein A-II)

Ortholog Status:

The human GeneID 336 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Alcw1	Acute Alcohol Withdrawal	1	96	172.3-176.5 (Mb)	5.6	3.00E-07	Significant	PARC
Calw1/Alcdp1	Chronic Alcohol Withdrawal	1	96	89-106.3 (cM)	7.6	2.00E-09	Significant	PARC
Ap1q	Alcohol Preference Drinking	1	76	45-95 (cM)	4.5		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_013474.2	NP_038502.2	NC_000067.5 range: 173155219..173156500

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	IDA (1596514\|6403543\|9186920)
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0005319	lipid transporter activity	Molecular Function	IEA
GO:0008035	high-density lipoprotein binding	Molecular Function	IMP (14729860)
GO:0008289	lipid binding	Molecular Function	IEA
GO:0042632	cholesterol homeostasis	Biological Process	IDA (8422330)
GO:0042632	cholesterol homeostasis	Biological Process	IMP (10357838)
GO:0042157	lipoprotein metabolic process	Biological Process	IDA (7837794\|9150245)
GO:0030300	regulation of cholesterol absorption	Biological Process	IMP (8962133)
GO:0042632	cholesterol homeostasis	Biological Process	IGI (10357838)
GO:0015759	beta-glucoside transport	Biological Process	NAS (12269810)
GO:0008203	cholesterol metabolic process	Biological Process	IMP (8647961\|10357838)
GO:0008203	cholesterol metabolic process	Biological Process	IGI (10357838)
GO:0006869	lipid transport	Biological Process	IMP (14729860)
GO:0006810	transport	Biological Process	IEA
GO:0006631	fatty acid metabolic process	Biological Process	NAS (12269810)
GO:0060192	negative regulation of lipase activity	Biological Process	IMP (10357838)