ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

336

Symbol:

APOA2

Full Name:

apolipoprotein A-II

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

1q21-q23

Physical Location:

159458706-159460041 on NC_000001.9, complement

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 11807 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

APOA2

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001643.1	NP_001634.1	NC_000001.9 range: 159458706..159460041, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0042627	chylomicron	Cellular Component	IDA (8245722)
GO:0005576	extracellular region	Cellular Component	EXP (4345202\|12692552)
GO:0005576	extracellular region	Cellular Component	NAS (14718574)
GO:0005615	extracellular space	Cellular Component	IDA (17264082)
GO:0005788	endoplasmic reticulum lumen	Cellular Component	EXP (12692552)
GO:0034190	apolipoprotein receptor binding	Molecular Function	IPI (11162594)
GO:0042803	protein homodimerization activity	Molecular Function	IDA (17264082)
GO:0046982	protein heterodimerization activity	Molecular Function	IPI (7918467)
GO:0008289	lipid binding	Molecular Function	IEA
GO:0008047	enzyme activator activity	Molecular Function	IDA (14967812)
GO:0005515	protein binding	Molecular Function	IPI (11991719)
GO:0005319	lipid transporter activity	Molecular Function	IEA
GO:0055102	lipase inhibitor activity	Molecular Function	IDA (14967812)
GO:0050748	negative regulation of lipoprotein metabolic process	Biological Process	IDA (11551871)
GO:0050995	negative regulation of lipid catabolic process	Biological Process	NAS (14967812)
GO:0051346	negative regulation of hydrolase activity	Biological Process	IDA (14967812)
GO:0045416	positive regulation of interleukin-8 biosynthetic process	Biological Process	IDA (11591715)
GO:0043691	reverse cholesterol transport	Biological Process	IDA (14967812)
GO:0042632	cholesterol homeostasis	Biological Process	IDA (14967812)
GO:0042158	lipoprotein biosynthetic process	Biological Process	IDA (14967812)
GO:0033700	phospholipid efflux	Biological Process	IDA (11162594)
GO:0033344	cholesterol efflux	Biological Process	IDA (11162594)
GO:0031647	regulation of protein stability	Biological Process	IDA (14967812)
GO:0009749	response to glucose stimulus	Biological Process	IDA (14988251)
GO:0008203	cholesterol metabolic process	Biological Process	IDA (14967812)
GO:0006869	lipid transport	Biological Process	IEA
GO:0006457	protein folding	Biological Process	IDA (14967812)
GO:0002740	negative regulation of cytokine secretion during immune response	Biological Process	IDA (12458630)