ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

SERPINA3

Full Name:

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3

Alias:

AACT|ACT|GIG24|GIG25|MGC88254

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

14q32.1

Physical Location:

94148466-94160142 on NC_000014.7

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 20716 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

SERPINA3

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001085.4	NP_001076.2	NC_000014.7 range: 94148466..94160142

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	TAS (14668352)
GO:0005622	intracellular	Cellular Component	NAS (9880565)
GO:0005576	extracellular region	Cellular Component	NAS (9880565\|14718574)
GO:0003677	DNA binding	Molecular Function	IC (9880565)
GO:0005515	protein binding	Molecular Function	IPI (12709365\|14668352\|14687906)
GO:0003677	DNA binding	Molecular Function	TAS (14668352)
GO:0030569	chymotrypsin inhibitor activity	Molecular Function	NAS (9880565)
GO:0006953	acute-phase response	Biological Process	IEA
GO:0006954	inflammatory response	Biological Process	NAS (12475184)
GO:0019216	regulation of lipid metabolic process	Biological Process	NAS (11835318)