ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Ckmt1

Full Name:

creatine kinase, mitochondrial 1, ubiquitous

Alias:

Mt-CK|ScCKmit|UbCKmit|mi-CK

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

2 F1-F3|2 67.6 cM

Physical Location:

121184376-121189472 on NC_000068.6

Gene Type:

protein-coding

Human Ortholog:

GeneID: 1159 Symbol (Name): CKMT1B (creatine kinase, mitochondrial 1B)

Ortholog Status:

The human GeneID 1159 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		AV091448
Note:		Differences expression between alcohol treatment and control groups

Dataset Information

Name:		15282116
Method:		Microarray
Tissue:		Striata
Phenotype:		Alcohol-nonpreferring, alcohol-preferring, alcohol self-administration
Publication:		Saito et al. Alcohol. (2004) Mouse striatal transcriptome analysis: effects of oral self-administration of alcohol. PubMed
Summary:		Aiming to define pathways among genomic, neural, and behavioral determinants of addiction, we investigated global striatal gene expression in a paradigm of oral self-administration of alcohol by using genomically very similar alcohol-nonpreferring B6.Cb(5)i(7)-alpha 3/Vad (C5A3) and alcohol-preferring B6.Ib(5)i(7)-beta 25A/Vad (I5B25A) quasi-congenic mouse strains and their progenitors, C57BL/6By (B6By) and BALB/cJ. Expression of 12,488 genes and expressed sequence tags (ESTs) was studied by using 24 high-density oligonucleotide microarrays. As expected, striatal transcriptome differences were far more extensive between the independently derived progenitor strains than between the quasi-congenic strains and their background partner, B6By.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_009897.2	NP_034027.1	NC_000068.6 range: 121184376..121189472

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005739	mitochondrion	Cellular Component	IDA (14651853)
GO:0016020	membrane	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0016740	transferase activity	Molecular Function	IEA
GO:0016301	kinase activity	Molecular Function	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0004111	creatine kinase activity	Molecular Function	IEA
GO:0003824	catalytic activity	Molecular Function	IEA
GO:0016772	transferase activity, transferring phosphorus-containing groups	Molecular Function	IEA