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Dataset Description
  • Dataset Name: 15282116
  • Species: Mouse
  • Method: Microarray
  • No. of Genes: 56
  • Tissue: Striata
  • Phenotype: Alcohol-nonpreferring, alcohol-preferring, alcohol self-administration
  • Publication: Saito et al. Alcohol. (2004) Mouse striatal transcriptome analysis: effects of oral self-administration of alcohol. PubMed
  • Dataset Summary: Aiming to define pathways among genomic, neural, and behavioral determinants of addiction, we investigated global striatal gene expression in a paradigm of oral self-administration of alcohol by using genomically very similar alcohol-nonpreferring B6.Cb(5)i(7)-alpha 3/Vad (C5A3) and alcohol-preferring B6.Ib(5)i(7)-beta 25A/Vad (I5B25A) quasi-congenic mouse strains and their progenitors, C57BL/6By (B6By) and BALB/cJ. Expression of 12,488 genes and expressed sequence tags (ESTs) was studied by using 24 high-density oligonucleotide microarrays. As expected, striatal transcriptome differences were far more extensive between the independently derived progenitor strains than between the quasi-congenic strains and their background partner, B6By.

    Gene list of this dataset (56 genes)
    Page: 1 2 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    14412Slc6a13solute carrier family 6 (neurotransmitter transporter, GABA), member 136 F1AA673769 
    77090Ocel1occludin/ELL domain containing 18 C1AA689927 
    114896Afg3l1AFG3(ATPase family gene 3)-like 1 (yeast)8 E1-E2AA797556 
    73824Snhg6small nucleolar RNA host gene (non-protein coding) 6-AA874329 
    19174Psmb5-psproteasome (prosome, macropain) subunit, beta type 5, pseudogene11 E1|11 60.0 cMAB003305 
    12371Casp9caspase 94 E1AB019600 
    54526Syt10synaptotagmin X15 F1AB026807 
    12804Cntfrciliary neurotrophic factor receptor4 A5|4 19.9 cMAF068615 
    12704Citcitron5 FAF086824 
    53625B3gnt2UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 211 A3.2|11 12.0 cMAF092050 
    94184Pdxdc1pyridoxal-dependent decarboxylase domain containing 116 A1AI180784 
    66687Tbc1d15TBC1 domain family, member 1510 D2AI194333 
    78785Clip4CAP-GLY domain containing linker protein family, member 417 E2AI504338 
    232879Zbtb45zinc finger and BTB domain containing 457 A1AI595382 
    110695Aldh7a1aldehyde dehydrogenase family 7, member A118 D3|18 29.0 cMAI835461 
    68183Bcas2breast carcinoma amplified sequence 23 F2.2AI838996 
    113868Acaa1aacetyl-Coenzyme A acyltransferase 1A9 F4|9 71.0 cMAI841705 
    94184Pdxdc1pyridoxal-dependent decarboxylase domain containing 116 A1AI843518 
    667764933439C20RikRIKEN cDNA 4933439C20 gene-AI845165 
    109229Ppp4r1lprotein phosphatase 4, regulatory subunit 1-like9 A5.3AI847282 
    233802Thumpd1THUMP domain containing 17 F2|7 59.0 cMAI851052 
    16413Itgb1bp1integrin beta 1 binding protein 112 A1.2AJ001373 
    23955Nek4NIMA (never in mitosis gene a)-related expressed kinase 414 BAJ223071 
    71853Pdia6protein disulfide isomerase associated 612 A1.1AW045202 
    239691AU021092expressed sequence AU02109216 A1AW045808 
    66184Rps4y2ribosomal protein S4, Y-linked 26 G3AW046496 
    68845Pih1d1PIH1 domain containing 17 B4AW048608 
    17434Mocs2molybdenum cofactor synthesis 213 D2.2AW060325 
    689361190017O12RikRIKEN cDNA 1190017O12 gene16 C4AW122061 
    68644Abhd14aabhydrolase domain containing 14A9 F1AW123271 
    59090Midnmidnolin10 C1AW124785 
    50706Postnperiostin, osteoblast specific factor3 CD13664 
    12890Cplx2complexin 213 B1D38613 
    17476Mpeg1macrophage expressed gene 119 AL20315 
    12039Bckdhabranched chain ketoacid dehydrogenase E1, alpha polypeptide-L47335 
    11482Acvrl1activin A receptor, type II-like 115 F3L48015 
    17527Mpv17Mpv17 transgene, kidney disease mutant5 B1M36411 
    11668Aldh1a1aldehyde dehydrogenase family 1, subfamily A119 B|19 12.0 cMM74570 
    13036Ctshcathepsin H9 E3.1|9 50.0 cMU06119 
    16524Kcnj9potassium inwardly-rectifying channel, subfamily J, member 91 H3|1 94.2 cMU11860 
    14688Gnb1guanine nucleotide binding protein (G protein), beta 14 E2|4 79.4 cMU29055 
    22608Ybx1Y box protein 14 D1U33196 
    22630Ywhaqtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide12 A1.3U56243 
    Page: 1 2 list all