Logo
Home Search BLAST Integration Document Link Support Citation

Gene Information
Gene ID:12890
Symbol:Cplx2
Full Name:complexin 2
Alias:921-L|AI413745|AW492120
Organism:Mus musculus (Mouse)
Chromosome:13
Genetic Location:13 B1
Physical Location:54472712-54485277 on NC_000079.5
Gene Type:protein-coding
Human Ortholog:GeneID: 10814    Symbol (Name): CPLX2 (complexin 2)
Ortholog Status:The human GeneID 10814 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:D38613
Note:Differences expression in alcohol-preferring and alcohol-nonpreferring mouse strains
Dataset Information
Name:15282116
Method:Microarray
Tissue:Striata
Phenotype:Alcohol-nonpreferring, alcohol-preferring, alcohol self-administration
Publication:Saito et al. Alcohol. (2004) Mouse striatal transcriptome analysis: effects of oral self-administration of alcohol. PubMed
Summary:Aiming to define pathways among genomic, neural, and behavioral determinants of addiction, we investigated global striatal gene expression in a paradigm of oral self-administration of alcohol by using genomically very similar alcohol-nonpreferring B6.Cb(5)i(7)-alpha 3/Vad (C5A3) and alcohol-preferring B6.Ib(5)i(7)-beta 25A/Vad (I5B25A) quasi-congenic mouse strains and their progenitors, C57BL/6By (B6By) and BALB/cJ. Expression of 12,488 genes and expressed sequence tags (ESTs) was studied by using 24 high-density oligonucleotide microarrays. As expected, striatal transcriptome differences were far more extensive between the independently derived progenitor strains than between the quasi-congenic strains and their background partner, B6By.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_009946.2NP_034076.1NC_000079.5 range: 54472712..54485277
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentIEA
GO:0019905syntaxin bindingMolecular FunctionIEA
GO:0006810transportBiological ProcessIEA
GO:0006836neurotransmitter transportBiological ProcessRCA (12466851)
GO:0006887exocytosisBiological ProcessIEA
GO:0006904vesicle docking during exocytosisBiological ProcessRCA (12466851)
GO:0006944membrane fusionBiological ProcessRCA (12466851)
GO:0007033vacuole organization and biogenesisBiological ProcessRCA (12466851)
GO:0043303mast cell degranulationBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:12890
MGI:
Ensembl:ENSMUSG00000025867
dbSNP:Cplx2
AceView:Cplx2