ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Postn

Full Name:

periostin, osteoblast specific factor

Alias:

AI747096|OSF-2|Osf2|PN|Periostin|peri

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

3 C

Physical Location:

54165046-54194953 on NC_000069.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 10631 Symbol (Name): POSTN (periostin, osteoblast specific factor)

Ortholog Status:

The human GeneID 10631 is also in human dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		D13664
Note:		Differences expression in alcohol-preferring and alcohol-nonpreferring mouse strains

Dataset Information

Name:		15282116
Method:		Microarray
Tissue:		Striata
Phenotype:		Alcohol-nonpreferring, alcohol-preferring, alcohol self-administration
Publication:		Saito et al. Alcohol. (2004) Mouse striatal transcriptome analysis: effects of oral self-administration of alcohol. PubMed
Summary:		Aiming to define pathways among genomic, neural, and behavioral determinants of addiction, we investigated global striatal gene expression in a paradigm of oral self-administration of alcohol by using genomically very similar alcohol-nonpreferring B6.Cb(5)i(7)-alpha 3/Vad (C5A3) and alcohol-preferring B6.Ib(5)i(7)-beta 25A/Vad (I5B25A) quasi-congenic mouse strains and their progenitors, C57BL/6By (B6By) and BALB/cJ. Expression of 12,488 genes and expressed sequence tags (ESTs) was studied by using 24 high-density oligonucleotide microarrays. As expected, striatal transcriptome differences were far more extensive between the independently derived progenitor strains than between the quasi-congenic strains and their background partner, B6By.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_015784.2	NP_056599.1	NC_000069.5 range: 54165046..54194953

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005578	proteinaceous extracellular matrix	Cellular Component	IDA (10404027)
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0005515	protein binding	Molecular Function	IEA
GO:0008201	heparin binding	Molecular Function	IDA (7663166)
GO:0007155	cell adhesion	Biological Process	IDA (10404027)
GO:0009888	tissue development	Biological Process	IMP (16314533)
GO:0030198	extracellular matrix organization and biogenesis	Biological Process	IMP (16314533)