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Gene Information
Gene ID:54526
Symbol:Syt10
Full Name:synaptotagmin X
Organism:Mus musculus (Mouse)
Chromosome:15
Genetic Location:15 F1
Physical Location:89612823-89672199 on NC_000081.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 341359    Symbol (Name): SYT10 (synaptotagmin X)
Ortholog Status:The human GeneID 341359 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:AB026807
Note:Differences expression in alcohol-preferring and alcohol-nonpreferring mouse strains
Dataset Information
Name:15282116
Method:Microarray
Tissue:Striata
Phenotype:Alcohol-nonpreferring, alcohol-preferring, alcohol self-administration
Publication:Saito et al. Alcohol. (2004) Mouse striatal transcriptome analysis: effects of oral self-administration of alcohol. PubMed
Summary:Aiming to define pathways among genomic, neural, and behavioral determinants of addiction, we investigated global striatal gene expression in a paradigm of oral self-administration of alcohol by using genomically very similar alcohol-nonpreferring B6.Cb(5)i(7)-alpha 3/Vad (C5A3) and alcohol-preferring B6.Ib(5)i(7)-beta 25A/Vad (I5B25A) quasi-congenic mouse strains and their progenitors, C57BL/6By (B6By) and BALB/cJ. Expression of 12,488 genes and expressed sequence tags (ESTs) was studied by using 24 high-density oligonucleotide microarrays. As expected, striatal transcriptome differences were far more extensive between the independently derived progenitor strains than between the quasi-congenic strains and their background partner, B6By.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_018803.1NP_061273.1NC_000081.5 range: 89612823..89672199, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016021integral to membraneCellular ComponentRCA (12466851)
GO:0045202synapseCellular ComponentIEA
GO:0031410cytoplasmic vesicleCellular ComponentIEA
GO:0008021synaptic vesicleCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0030054cell junctionCellular ComponentIEA
GO:0005215transporter activityMolecular FunctionIEA
GO:0005509calcium ion bindingMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0006810transportBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:54526
MGI:
Ensembl:ENSMUSG00000063260
dbSNP:Syt10
AceView:Syt10