ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Slc6a13

Full Name:

solute carrier family 6 (neurotransmitter transporter, GABA), member 13

Alias:

GAT3|Gabt3

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

6 F1

Physical Location:

121250313-121287735 on NC_000072.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 6540 Symbol (Name): SLC6A13 (solute carrier family 6 (neurotransmitter transporter, GABA), member 13)

Ortholog Status:

The human GeneID 6540 is also in human dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		AA673769
Note:		Differences expression in alcohol-preferring and alcohol-nonpreferring mouse strains

Dataset Information

Name:		15282116
Method:		Microarray
Tissue:		Striata
Phenotype:		Alcohol-nonpreferring, alcohol-preferring, alcohol self-administration
Publication:		Saito et al. Alcohol. (2004) Mouse striatal transcriptome analysis: effects of oral self-administration of alcohol. PubMed
Summary:		Aiming to define pathways among genomic, neural, and behavioral determinants of addiction, we investigated global striatal gene expression in a paradigm of oral self-administration of alcohol by using genomically very similar alcohol-nonpreferring B6.Cb(5)i(7)-alpha 3/Vad (C5A3) and alcohol-preferring B6.Ib(5)i(7)-beta 25A/Vad (I5B25A) quasi-congenic mouse strains and their progenitors, C57BL/6By (B6By) and BALB/cJ. Expression of 12,488 genes and expressed sequence tags (ESTs) was studied by using 24 high-density oligonucleotide microarrays. As expected, striatal transcriptome differences were far more extensive between the independently derived progenitor strains than between the quasi-congenic strains and their background partner, B6By.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_144512.2	NP_653095.1	NC_000072.5 range: 121250313..121287735

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005887	integral to plasma membrane	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0005328	neurotransmitter:sodium symporter activity	Molecular Function	IEA
GO:0005332	gamma-aminobutyric acid:sodium symporter activity	Molecular Function	IEA
GO:0015293	symporter activity	Molecular Function	IEA
GO:0006810	transport	Biological Process	IEA
GO:0006836	neurotransmitter transport	Biological Process	IEA